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From one well to 9000: using high-density streptavidin-coated membranes for kinase detection
Michael Curtin1, John Watson, Said Goueli
1Promega Corporation, Madison, WI 53711, USA. mcurtin@promega.com
Biotechniques
|October 25, 2002
Abstract:
The study of kinases and their role in cellular regulation continues to expand as the human genome is sequenced and new kinases are identified as expression products of newly discovered genes. Reagents and assay systems that allow for sensitive, accurate, and high-throughput analysis of both purified kinases as well as crude extracts will enhance the characterization of these important cellular components and will speed the identification of appropriate therapeutic targets and the development of new and more effective treatments.