Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Direct cardiac compression devices.

Mehmet C Oz1, John H Artrip, Daniel Burkhoff

  • 1Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. mco2@columbia.edu

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
|October 26, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Right Ventricular Metrics as End Points in Clinical Trials: A Review.

JAMA cardiology·2026
Same author

Comprehensive Clinical Benefit of CCM in HFrEF Patients - a win-ratio analysis of FIX-HF-5C randomized trial.

ESC heart failure·2026
Same author

Universal Pulmonary Resistance-Compliance Relationship: And Why It Matters?

Circulation. Heart failure·2026
Same author

De Novo Aortic Insufficiency and Its Progression in Patients on Microaxial Flow Pump Support Before Durable Left Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

Cardiac microcurrent therapy in heart failure: Mechanistic rationale, early clinical evidence, and future directions.

Heart failure reviews·2026
Same author

Does Pacemaker Mode Affect Outcomes in Patients With HeartMate 3 LVAD?

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Distinct Metabolomic and Lipidomic Profiles Across Donation after Circulatory Death Recovery Strategies Reveal a Common Signature Associated with Primary Graft Dysfunction.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

Antibody-mediated rejection after heart transplantation: diagnostic gaps, suboptimal outcomes, and emerging tools.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

What sotatercept can teach us about the right ventricle in pulmonary arterial hypertension.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

The Future of Heart Transplant Data Science Requires Common Data Models.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

From Guideline to Practice: Operationalizing Telomere Length Testing in ILD and Lung Transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same journal

A Two-Threshold dd-cfDNA Algorithm Improves Detection of Molecular Rejection in Heart Transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
See all related articles

Direct cardiac compression (DCC) offers ventricular support by avoiding blood-device contact, unlike traditional ventricular assist devices. This approach may reduce complications like clots and infections associated with current heart support technologies.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Medical Devices

Background:

  • Current ventricular assist devices (VADs) interact directly with blood, leading to significant complications.
  • Thromboembolic events, hemolysis, immune reactions, and infections are major causes of morbidity and mortality with VADs.

Purpose of the Study:

  • To review the physiology of epicardial compression for ventricular support.
  • To discuss the progress of mechanical direct cardiac compression (DCC) devices.

Main Methods:

  • Review of existing literature on epicardial compression.
  • Analysis of physiological principles underlying cardiac compression.
  • Survey of current mechanical DCC device development.

Related Experiment Videos

Main Results:

  • Direct cardiac compression (DCC) avoids blood-device interface, potentially mitigating VAD-related complications.
  • Epicardial compression offers a novel approach to mechanical circulatory support.

Conclusions:

  • Direct cardiac compression presents a promising alternative to transcutaneous ventricular assist devices.
  • Further development of DCC devices could improve outcomes for patients with heart failure.