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Histone-like proteins and the Shigella invasivity regulon
Gianni Prosseda1, Maurizio Falconi, Mauro Nicoletti
1Dip Biologia Cellulare e dello Sviluppo, Università La Sapienza, Rome, Italy.
Research in Microbiology
|October 31, 2002
Abstract:
The contribution of histone-like proteins to the transcriptional regulation of virulence gene networks is a common feature among pathogenic bacteria. In this article we review current knowledge about the regulative role of major histone-like proteins in the silencing/activation of the invasivity phenotype of Shigella, the etiological agent of bacillary dissentery.