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[Pterygoid corneal dystrophy].

Eva Wolter-Roessler1, Berthold Seitz, Gottfried O H Naumann

  • 1Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen, Germany.

Klinische Monatsblatter Fur Augenheilkunde
|November 1, 2002
PubMed
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This study describes a rare, inherited form of pterygium affecting three family members. The condition, termed "pterygoid corneal dystrophy," shows aggressive recurrences after surgery.

Area of Science:

  • Ophthalmology
  • Genetics

Background:

  • Pterygia involve fibrovascular tissue growth onto the cornea, potentially causing vision loss.
  • This report details a family with bilateral, symmetrical pterygium-like changes affecting nasal and temporal limbus.

Observation:

  • Three family members presented with pterygium-like corneal changes.
  • The condition affected nasal and temporal limbus bilaterally and symmetrically.
  • Surgical excisions, including lamellar keratoplasty, resulted in persistent, aggressive recurrences.

Findings:

  • Histological examination revealed elastoid degeneration of collagen fibers.
  • Autosomal dominant inheritance with variable expression is suspected for this condition.
  • The histological features resemble typical pterygia.

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Implications:

  • This familial condition, termed "pterygoid corneal dystrophy," may represent a distinct entity due to its aggressive recurrence rate.
  • Understanding the genetic basis and aggressive nature is crucial for patient management and treatment strategies.