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Psychopharmacological profiles of Leucas Lavandulaefolia Rees
Kakali Mukherjee1, B P Saha, Pulok K Mukherjee
1Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700032, India. mukherjeepk@rediffmail.com
Phytotherapy Research : PTR
|November 1, 2002
Abstract:
Methanol extract of Leucas lavandulaefolia (LLFE) was evaluated for different psychopharmacological profiles with various animal models in rats and mice. The extract showed a potential reduction in spontaneous activity and caused a significant decrease in exploratory behavioural pattern by the head dip and Y-maze test. It also showed a significant reduction in muscle relaxant activity by rotarod, 30 degrees inclined screen and traction tests. The extract showed a remarkable potentiation of pentobarbitone induced sleeping time in mice.