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Treatment of vaginal agglutination associated with chronic graft-versus-host disease
1Emory University School of Medicine, Atlanta, Georgia, USA. ehayes2@emory.edu
Objective:
To describe the presentation and clinical course of two patients after development of vaginal agglutination associated with chronic graft-versus-host disease.
Design:
Case report.
Setting:
Tertiary referral center for pelvic reconstructive surgery.
Patient(S):
Two patients with the diagnosis of chronic graft-versus-host disease who later developed vaginal agglutination requiring treatment.
Intervention(S):
Surgical lysis of vaginal adhesions and postoperative use of vaginal dilators.
Main Outcome Measure(S):
Successful treatment of vaginal adhesions.
Result(S):
Both patients underwent successful surgical lysis of vaginal adhesions and maintained vaginal patency with postoperative use of vaginal dilators.
Conclusion(S):
Prompt diagnosis of vaginal agglutination in patients with chronic graft-versus-host disease and appropriate surgical correction of this complication rather than prophylaxis is the correct treatment course.