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Panniculitides--a clinicopathologic study.
1Department of Medicine, All India Institute of Medical Sciences, New Delhi.
The Journal of the Association of Physicians of India
|November 8, 2002
Summary
Panniculitis is uncommon in India. Erythema nodosum is the most frequent type, often responding to NSAIDs, while other forms require corticosteroids. Early diagnosis relies on clinical and histopathological assessment.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Panniculitides are uncommon inflammatory conditions affecting subcutaneous fat.
- Limited Indian literature exists on the clinical and pathologic spectrum of panniculitis.
Purpose of the Study:
- To delineate the clinical and pathologic characteristics of panniculitis in North India.
- To address the paucity of data on panniculitis in the Indian subcontinent.
Main Methods:
- Prospective study over four years.
- Inclusion of patients presenting with panniculitis at a North Indian teaching hospital.
Main Results:
- Erythema nodosum (EN) constituted 79.3% of cases.
- Other diagnoses included erythema induratum, Weber Christian disease, and vasculitides.
- Septal panniculitis without vasculitis was the predominant histopathologic pattern.
- Elevated ESR and leukocytosis were common laboratory findings.
Conclusions:
- Clinical recognition and histopathological confirmation are crucial for diagnosing and managing panniculitis.
- Physician awareness is key to identifying these uncommon conditions.