Glucorrhea revisited. Prolonged promulgation of another plastic pearl

JAMA
|December 8, 1975
PubMed

Insights

Glucose oxidase test strips detected significant glucose in nasal secretions and tears of children. This finding indicates these tests are unreliable for diagnosing cerebrospinal fluid rhinorrhea.

Area of Science:

  • Biochemistry
  • Pediatrics
  • Ophthalmology

Background:

  • Cerebrospinal fluid (CSF) rhinorrhea is a serious condition requiring accurate diagnosis.
  • Glucose detection in nasal secretions is a potential diagnostic method.

Observation:

  • Glucose oxidase test strips were employed to measure glucose levels in nasal secretions and tears.
  • Samples were collected from a cohort of healthy children.

Findings:

  • Elevated glucose concentrations were identified in 15 out of 17 nasal discharge samples.
  • Glucose was also detected in 10 out of 15 tear samples.

Implications:

  • The presence of glucose in nasal secretions and tears is common in children.
  • Glucose oxidase test strips lack the specificity for diagnosing CSF rhinorrhea.
  • Alternative diagnostic methods for CSF rhinorrhea should be considered.

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