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Related Experiment Videos

Pursuit speed compensation in cortical area MSTd.

Krishna V Shenoy1, James A Crowell, Richard A Andersen

  • 1Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.

Journal of Neurophysiology
|November 9, 2002
PubMed
Summary

The dorsal medial superior temporal area (MSTd) in macaques compensates for eye movements during self-motion perception. Neurons in MSTd adjust their focus tuning more at faster pursuit speeds, indicating accurate heading estimation regardless of speed.

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Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Vision Science

Background:

  • Humans estimate self-motion (heading) using the focus of expansion (FOE) in retinal images.
  • Smooth pursuit eye movements shift the FOE, complicating heading perception.
  • The dorsal medial superior temporal area (MSTd) is implicated in correcting for pursuit during egomotion estimation.

Purpose of the Study:

  • To investigate if MSTd neurons compensate for increasing pursuit speeds.
  • To determine the contribution of retinal and extraretinal cues to pursuit compensation in MSTd.
  • To explore how MSTd neurons combine visual and eye movement information for accurate heading perception.

Main Methods:

  • Recorded neural activity from 40 MSTd neurons in macaque monkeys.

Related Experiment Videos

  • Monkeys performed smooth pursuit eye movements at various speeds across simulated motion displays.
  • Compared neural responses during real pursuit with a simulated pursuit condition using counter-rotating displays.

    • Main Results:

    • MSTd neurons increased focus tuning compensation with faster pursuit speeds.
    • Retinal cues contributed 30% to pursuit compensation.
    • Extraretinal cues significantly contributed to pursuit compensation, with a combined rate of 51% of perfect compensation.
    • A systematic antialignment between preferred pursuit and visual motion directions was observed.

    Conclusions:

    • MSTd neurons compensate for pursuit velocity, direction, and speed, crucial for egomotion.
    • Both retinal and extraretinal cues are integrated in MSTd for accurate heading perception.
    • MSTd plays a critical role in computing self-motion perception during active vision.