Covariation of the simultaneously recorded c-wave and standing potential of the human eye

The c-wave and the directly recorded standing potential (SP) of the human eye were studied with the aid of a recently developed method including matched temperature stabilized calomel electrodes, d.c. amplifiers and a suction contact lens. This technique, which does not require general anaesthesia, permits simultaneous direct d.c. recordings of the SP and the c-wave in human volunteers during long-term experiments. Upon repetitive light flashes (stimulus duration 1 sec, interval 20 sec and flash intensity 4.5 rel. log units above b-wave threshold) both variables responded with slow amplitude oscillations with a frequency of about 2/hour. The oscillations were similar as to phases and frequencies. Both the potentials are held to be generated mainly in the pigment epithelium. Considering this partly common origin the observed covariation was an interesting finding.