Related Experiment Video
Updated: Aug 9, 2026

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
Published on: January 17, 2011
Esophageal perforation associated with noninvasive ventilation: a case report
Andry Van de Louw1, Elsa Brocas, Richard Boiteau
1Service de réanimation polyvalente, Hôpital Louise Michel, Centre Hospitalier Sud Francilien, Evry Cedex, France. a.vandelouw@infonie.fr
Noninvasive positive-pressure ventilation (NIPPV) can help avoid tracheal intubation for respiratory failure. However, a rare case shows NIPPV can lead to fatal esophageal perforation.
Area of Science:
- Medicine
- Pulmonology
- Critical Care
Background:
- Noninvasive positive-pressure ventilation (NIPPV) is a common treatment for acute respiratory failure, aiming to prevent tracheal intubation and its associated complications.
- While generally safe and effective in reducing intubation rates, morbidity, and mortality in specific patient groups, potential adverse events require ongoing vigilance.
Observation:
- This report details a rare and fatal case of esophageal perforation.
- The complication occurred in a patient following a surgical procedure while receiving NIPPV.
Findings:
- Esophageal perforation, a known risk of tracheal intubation, has not been previously documented with NIPPV.
- This case highlights a potentially fatal, previously undescribed complication of NIPPV.
Implications:
- Clinicians should be aware of the potential for esophageal perforation as a rare complication of NIPPV.
- Further investigation may be warranted to understand the mechanisms and risk factors for NIPPV-associated esophageal injury.
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:

