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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
[Toxocariasis - an underestimated problem in paediatrics]
Kamil Hozyasz1, Andrzej Milanowski
1Klinika Pediatrii, Instytut Matki i Dziecka, ul. Kasprzaka 17a, Warszawa, Poland. khozyasz@alpha.net.pl
Insights
Human toxocariasis, a parasitic infection from pet roundworms, is common in children due to environmental contamination. Early diagnosis and treatment are crucial for managing this widespread zoonotic disease.
Area of Science:
- Veterinary Parasitology
- Pediatric Infectious Diseases
- Environmental Health
Background:
- Human toxocariasis results from infection with zoonotic roundworms (Toxocara spp.) found in dogs and cats.
- Widespread environmental contamination with Toxocara eggs, particularly in children's play areas, poses a significant public health risk.
- Seroprevalence rates in children vary regionally, with higher rates observed in South-East Poland (19%) compared to West Poland (3.5%).
Observation:
- Children are at higher risk due to close contact with contaminated soil and geophagia.
- A case of covert toxocariasis in a 3-year-old girl presented without classic symptoms, highlighting diagnostic challenges.
- Initial blood work revealed significant leukocytosis (43x10(3)/mm3) and hyperosinophilia (81%).
Findings:
- The patient was treated with albendazole, with repeated treatment after one year.
- Long-term follow-up (1.5 years) showed persistently positive serological tests for Toxocara canis.
- Blood counts improved but remained elevated (lowest 20.0x10(3)/mm3) with persistent eosinophilia (19%).
Implications:
- Covert toxocariasis can manifest without typical visceral, ocular, or neurological signs, necessitating broader diagnostic considerations.
- Persistent eosinophilia in toxocariasis may be linked to the development of allergic and cardiovascular diseases.
- Effective treatment and monitoring are essential for managing toxocariasis and understanding its long-term health impacts.
Abstract:
Aspects of Toxocara spp. epidemiology and paratenic infestation of children are described. Human toxocariasis is caused by infestation of zoonotic roundworms of dogs and cats. Soil sampling showes widespread contamination of the environment, particularly parks and playgrounds, with the eggs of Toxocara spp. Toxocara seroprevelance values in children vary between 3.5% in the West Poland and 19% in the South-East Poland. Children more frequently have clinical symptoms o the disease because of the closer contact with contaminated soil in sand-boxes and relatively frequent geophagia. A 3 years old girl with covert toxocariasis is described. As this case illustrates, this disease can be present without its classic visceral, ocular or neurological manifestations. On admission to the hospital the results of blood tests were as follows: white blood cells count, 43x10(3)/ mm3 (norm <13x10(3)) and hyperosinophilia, 81%. The girl was treated with albendazole 15 mg/kg for five days, after one year the treatment was repeated. The patient was followed with blood samples throughout a period of one and half year. During that time results of serological tests for Toxocara canis were strongly positive. The lowest blood count was 20.0x10(3)/mm3 and eosinophilia, 19%. Possible association between high eosinophilia in toxocariasis and development of allergic and cardiovascular diseases is discussed.
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