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Enantioselective total synthesis of (-)-xialenon A
David M Hodgson1, Jean-Marie Galano, Martin Christlieb
1Dyson Perrins Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, UK OX1 3QY. david.hodgson@chem.ox.ac.uk
Chemical Communications (Cambridge, England)
|November 15, 2002
Abstract:
The first total synthesis of (-)-xialenon A (1) via conjugate allylation of a 1,5-cyclooctadiene-derived bicyclo[3.3.0]octenone 3 and an alpha'-hydroxylation on the more hinderd face of enone 9 using hypervalent iodine chemistry, is described.