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Polarized Translocation of Fluorescent Proteins in Xenopus Ectoderm in Response to Wnt Signaling
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The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development

Annette G M Borchers1, Andrew L Hufton, Adam G Eldridge

  • 1Department of Genetics, Stanford University, Stanford, CA 94305, USA.

Developmental Biology
|November 19, 2002
PubMed
Summary

Goliath Related E3 Ubiquitin Ligase 1 (GREUL1) converts ectoderm into anterior cell fates and acts as an E3 ubiquitin ligase. Its RING domain is crucial for both ubiquitination and anterior cell fate determination.

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