Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative analysis of micrographs by computer graphics.

R F Dunn, D P O'Leary, W E Kumley

    Journal of Microscopy
    |November 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Primary hyperparathyroidism causing posterior reversible encephalopathy syndrome: a case report.

    Annals of the Royal College of Surgeons of England·2021
    Same author

    Role of circulating fibrocytes in the diagnosis of acute appendicitis.

    BJS open·2020
    Same author

    Longer small bowel segments are resected in emergency surgery for ileocaecal Crohn's disease with a higher ileostomy and complication rate.

    Techniques in coloproctology·2019
    Same author

    The effect of purse-string approximation versus linear approximation of ileostomy reversal wounds on morbidity rates and patient satisfaction: the 'STOMA' trial.

    Techniques in coloproctology·2017
    Same author

    Clinical assessment to determine the risk of bowel cancer using Symptoms, Age, Mass and Iron deficiency anaemia (SAMI).

    The British journal of surgery·2017
    Same author

    Identification of the optimal visual recording system in open abdominal surgery - a prospective observational study.

    Journal of visual communication in medicine·2016
    Same journal

    In operando imaging of the space-charge region in a 4H-SiC MOSCAP using STEM-EBIC.

    Journal of microscopy·2026
    Same journal

    The future of DXA: How AI is transforming bone health diagnostics.

    Journal of microscopy·2026
    Same journal

    The Origins of Ploem's Filter Cube: A Pandora's Box.

    Journal of microscopy·2026
    Same journal

    The reproducibility gap in graph neural network workflows for cell dynamics: A checklist-driven case study.

    Journal of microscopy·2026
    Same journal

    Assessing the reproducibility of a bioimage analysis workflow characterising tissue flow in Drosophila.

    Journal of microscopy·2026
    Same journal

    Modular training resources for bioimage analysis.

    Journal of microscopy·2026
    See all related articles

    This study introduces a computer-aided system to analyze peripheral nerve micrographs, quantifying axon and myelin diameters, and fiber distribution. The system offers a novel, automated approach for detailed nerve structure analysis.

    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Computational Biology

    Background:

    • Peripheral nerve structure analysis is crucial for understanding neurological conditions.
    • Manual quantification of nerve micrographs is time-consuming and prone to error.

    Purpose of the Study:

    • To develop and present a computer-aided graphical analysis system for quantifying peripheral nerve micrograph data.
    • To automate the measurement of axon and myelin diameters, myelin thickness, and nerve fiber distribution.

    Main Methods:

    • A system utilizing eight input points per axon to measure diameters (axon, axon+myelin).
    • Computation of statistical estimates, myelin thickness as a function of axon diameter, and spatial fiber distribution.
    • Description of data digitization, editing, and analysis computer programs.

    Related Experiment Videos

    Main Results:

    • The system quantifies multiple parameters from peripheral nerve cross-sections.
    • It provides statistical and numerical estimates of diameters and myelin thickness.
    • Spatial position and distribution of nerve fibers within the bundle are determined.

    Conclusions:

    • The presented system offers an automated and efficient method for analyzing peripheral nerve micrographs.
    • This approach can be generalized for automated analysis in other anatomical regions.
    • The system enhances the quantitative analysis of nerve fiber morphology and organization.