[Tuberculosis control and strategy as an urban problem]
Related Experiment Video
Updated: Sep 28, 2026

Identification of Potential Anti-TB Candidates: A Step-by-Step Guide to Synthesis, MIC Determination, and Cytotoxicity Assessment in Mammalian Cells
Published on: May 22, 2026
1Department of Social and Environmental Health, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita-shi, Osaka 565-0871, Japan. tori@pbhel.med.osaka-u.ac.jp
Abstract:
Tuberculosis is always an urban problem. There are differences in the severity of pulmonary tuberculosis in relation to socio-economic groups. The percentages of cases shown to be positive by smear microscopy of acid-fast bacilli in their sputum specimens and of cases with cavitary lesions in the lungs were high for the lower socio-economic group. The percentage of cases having had chest X-ray examination within the preceding year was low for the lower socioeconomic group. The Osaka metropolitan area consists of many prefectures and cities. Osaka City is in the center of this great metropolis. Registered cases of each zone had statistically differences about social characteristics. This result was thought to reflect the population of each zone. Cooperative common political will against tuberculosis in this area is needed to promote tuberculosis control. We analyzed the incidence rate in Osaka City in five-year from 1978 to 1997. Until the first half of 1980, the tuberculosis incidence rate in Osaka City had been dropping every year, but the rate of decline has been slowed substantially or even stopped since 1983. The slowdown in the reduction of the tuberculosis incidence rate has occurred not in all wards, but in a few wards and it is a typical phenomenon of the middle-aged in those wards. Such tuberculosis among employees in an insecure position has a growing urban social problem. It is important to establish the cooperation between medical facilities and public health centers within the territory of tuberculosis hospitals in an urban area. The sources of tuberculosis infection in an urban area are quite diverse and complicated. We shall utilize a molecular epidemiologic analysis of Mycobacterium tuberculosis.
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
