Related Experiment Video
Updated: Aug 9, 2026

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Lateral connectivity and contextual interactions in macaque primary visual cortex
Dan D Stettler1, Aniruddha Das, Jean Bennett
1The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
Abstract:
Two components of cortical circuits could mediate contour integration in primary visual cortex (V1): intrinsic horizontal connections and feedback from higher cortical areas. To distinguish between these, we combined functional mapping with a new technique for labeling axons, a recombinant adenovirus bearing the gene for green fluorescent protein (GFP), to determine the extent, density, and orientation specificity of V1 intrinsic connections and V2 to V1 feedback. Both connections cover portions of V1 representing regions of visual space up to eight times larger than receptive fields as classically defined, though the intrinsic connections are an order of magnitude denser than the feedback. Whereas the intrinsic connections link similarly oriented domains in V1, V2 to V1 feedback displays no such specificity. These findings suggest that V1 intrinsic horizontal connections provide a more likely substrate for contour integration.
Related Concept Videos
Vision
Neural Circuits
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Somatosensory, Motor, and Association Cortex
Parallel Processing

