Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Insulating behavior of lambda-DNA on the micron scale.

Y Zhang1, R H Austin, J Kraeft

  • 1Department of Physics, Princeton University, Princeton, New Jersey 08544, USA.

Physical Review Letters
|November 22, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anomalous superconductivity in twisted MoTe<sub>2</sub> nanojunctions.

Science advances·2025
Same author

Charge-neutral electronic excitations in quantum insulators.

Nature·2024
Same author

Toward 1D Transport in 3D Materials: SOC-Induced Charge-Transport Anisotropy in Sm<sub>3</sub>ZrBi<sub>5</sub>.

Advanced materials (Deerfield Beach, Fla.)·2024
Same author

Chemical Bonding Induces One-Dimensional Physics in Bulk Crystal BiIr<sub>4</sub>Se<sub>8</sub>.

Journal of the American Chemical Society·2024
Same author

Anisotropic resistance with a 90° twist in a ferromagnetic Weyl semimetal, Co<sub>2</sub>MnGa.

Nature communications·2023
Same author

Planar thermal Hall effect of topological bosons in the Kitaev magnet α-RuCl<sub>3</sub>.

Nature materials·2022
Same journal

Erratum: Bacterial Turbulence at Compressible Fluid Interfaces [Phys. Rev. Lett. 136, 138301 (2026)].

Physical review letters·2026
Same journal

Unveiling Light-Quark Yukawa Flavor Structure via Dihadron Fragmentation at Lepton Colliders.

Physical review letters·2026
Same journal

Adaptable Route to Fast Coherent State Transport via Bang-Bang-Bang Protocols.

Physical review letters·2026
Same journal

Topological Transition and Emergence of Elasticity of Dislocation in Skyrmion Lattice: Beyond Kittel's Magnetic-Polar Analogy.

Physical review letters·2026
Same journal

Pound-Drever-Hall Method for Superconducting-Qubit Readout.

Physical review letters·2026
Same journal

Coupling a ^{73}Ge Nuclear Spin to an Electrostatically Defined Quantum Dot in Silicon.

Physical review letters·2026
See all related articles

We measured the electrical conductivity of lambda-DNA, finding it has very low conductivity (resistivity > 10^6 Ohm cm). Our results challenge previous claims and highlight the need to remove salt residues for accurate DNA conductivity measurements.

Area of Science:

  • Molecular Biophysics
  • Nanotechnology
  • Electrical Engineering

Background:

  • Understanding DNA's electrical properties is crucial for nanoelectronic applications.
  • Previous studies have reported conflicting results regarding DNA conductivity.
  • Accurate measurements require careful control of experimental conditions, including salt concentration.

Purpose of the Study:

  • To investigate the electrical conductivity of bacteriophage lambda-DNA.
  • To provide a reliable lower bound for DNA resistivity.
  • To address discrepancies in existing literature on DNA conductivity.

Main Methods:

  • Covalent bonding of lambda-DNA to gold electrodes via thiol-modified dTTP incorporation.
  • Two-probe electrical resistivity measurements at various bias potentials.

Related Experiment Videos

  • Direct imaging to confirm molecule presence post-measurement.

    • Main Results:

    • Determined a hard lower bound for lambda-DNA resistivity to be greater than 10^6 Ohm cm.
    • Results contradict recent reports suggesting moderate to high DNA conductivity.
    • Confirmed the presence of DNA molecules after measurements, validating the experimental setup.

    Conclusions:

    • Lambda-DNA exhibits significantly low electrical conductivity.
    • Experimental artifacts, such as salt residues, can significantly influence conductivity measurements.
    • Careful sample preparation and measurement protocols are essential for accurate assessment of DNA's electronic properties.