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Friedel-Crafts type reaction of ferrocene with beta-ketoesters
Damian Plazuk1, Janusz Zakrzewski
1Department of Organic Chemistry, University of Lodz, 90-136 Lodz, Narutowicza 68, Poland. janzak@krysia.uni.lodz.pl
The Journal of Organic Chemistry
|November 26, 2002
Abstract:
The reaction of ferrocene with beta-ketoesters in the presence of BF3.Et2O or CF3SO3H affords beta-ferrocenyl-alpha,beta-unsaturated esters in 56-83% yield. In the case of alpha-unsubstituted-beta-ketoesters the reaction is totally E-stereoselective.