Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Magnetic resonance imaging and deep brain stimulation.

Ryan J Uitti1, Yoshio Tsuboi, Robert A Pooley

  • 1Department of Neurology, Mayo Clinic, Jacksonville, Florida, FL 32224, USA.

Neurosurgery
|November 26, 2002
PubMed
Summary

Cranial magnetic resonance imaging (MRI) did not cause significant deep brain stimulation (DBS) lead displacement or program interference in patients. This finding suggests MRI may be safe for individuals with these implanted systems.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Dynamics of Polyglutamine-Expanded ATXN3 in Biofluids of Spinocerebellar Ataxia Type 3.

Movement disorders : official journal of the Movement Disorder Society·2026
Same author

MR Imaging Protocols for Epilepsy.

Neuroimaging clinics of North America·2026
Same author

Nuclear Imaging of Epilepsy.

Neuroimaging clinics of North America·2026
Same author

A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions.

Nature genetics·2026
Same author

Novel Aggressive Subtype of Multiple System Atrophy Identified by Unsupervised Machine Learning.

Annals of neurology·2026
Same author

Clinical 7T MRI for Epilepsy: A Retrospective Review of 50 Cases.

AJNR. American journal of neuroradiology·2025

Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Deep brain stimulation (DBS) is a crucial therapy for neurological disorders.
  • The safety of magnetic resonance imaging (MRI) in patients with implanted DBS systems is a significant clinical concern.
  • Lead displacement and program interference are potential risks during MRI in DBS patients.

Purpose of the Study:

  • To evaluate the association between cranial MRI and deep brain stimulation (DBS) lead displacement.
  • To assess the impact of MRI on DBS system program interference and clinical efficacy.
  • To determine the safety of MRI in patients with implanted DBS devices.

Main Methods:

  • In vitro and in vivo studies were conducted using specific DBS hardware (Itrel II IPG, Medtronic 3387/3389 leads) and a 1.5-T GE MRI scanner.

Related Experiment Videos

  • In vivo analysis involved comparing pre- and post-implantation volumetric MRI data in five patients to measure lead movement.
  • In vitro experiments systematically assessed lead and IPG behavior within the MRI magnetic field.

    • Main Results:

    • In vivo, 88% of lead deviations were within the measurement error (1.4 mm), with a maximum deviation of 3 mm in 2% of cases.
    • No significant changes in tremor control or clinical response were observed post-MRI.
    • In vitro, DBS leads showed no deflection, and no changes in IPG battery, lead impedance, or program settings occurred.

    Conclusions:

    • Cranial MRI is not associated with significant deep brain stimulation electrode movement or altered clinical outcomes.
    • Further research is needed to evaluate other IPG models, components, and MRI scanners.
    • Specific guidelines for MRI use in patients with implanted DBS systems are recommended.