[Treatment of patients with perforative gastroduodenal ulcer]

Social and medical aspects of unsatisfactory results of treatment of patients with perforative gastroduodenal ulcer (GDU) were analyzed. There was shown, that social reasons cause not only untimely diagnosis of this severe complication, but they are also slowing down the elaboration and improvement of pathogenetically substantiated methods of operative intervention. While analyzing results of surgical treatment of 590 patients with perforative GDU, of whom in 53 truncal vagotomy was performed, in 241--selective vagotomy, in 296--selective proximal (SPV), there was established, that SPV under condition of serotonin adipinate application in early postoperative period, influencing the gut smooth muscles, constitutes most effective operative intervention.