Glycosaminoglycans--all round talents in coating technology

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P Hildebrandt1

  • 1UroNova GmbH Medizinische Implantate, Erlangen, Germany. p.hildebrandt@uronova.de

Biomedizinische Technik. Biomedical Engineering
|November 28, 2002
PubMed

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Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
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