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Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
Published on: November 27, 2016
MRI of perforated gall bladder
Bimal Sood1, Manoj Jain, Niranjan Khandelwal
1Department of Medical Imaging, University of Queensland, Toowoomba Base Hospital, Australia. bimal_sood@health.qld.gov.au
Abstract:
Gall bladder perforation is a dreaded complication of acute cholecystitis that, if not diagnosed early in the course, might have a poor prognosis. Both CT and ultrasonography have been used until now extensively for the diagnosis of acute cholecystitis, but diagnosis of perforation is always difficult. Magnetic resonance, by its superior soft tissue resolution and multiplanar capability, is a better modality and should fare better than ultrasonography and CT, as demonstrated in our case. Magnetic resonance imaging demonstrates the wall of the gall bladder and defects to a much better advantage and more convincingly. In addition, MR colangiopancreatography images demonstrate the biliary tree better than other modalities. We suggest that in the case of acute cholecystitis, if perforation is suspected and CT and ultrasonography are not conclusive, MR should be the modality of choice. It can be used as a first line of investigation; however, it might not be cost-effective.
Insights
Gall bladder perforation, a severe complication of acute cholecystitis, is challenging to diagnose. Magnetic resonance imaging (MRI) offers superior visualization for detecting gallbladder perforation when CT and ultrasound are inconclusive.
Area of Science:
- Gastroenterology and Hepatobiliary Imaging
- Diagnostic Radiology
Background:
- Acute cholecystitis can lead to gallbladder perforation, a serious complication with significant morbidity.
- Early diagnosis of gallbladder perforation is crucial for improving patient prognosis.
- Conventional imaging modalities like CT and ultrasonography often face limitations in definitively diagnosing perforation.
Observation:
- Magnetic resonance (MR) imaging provides superior soft tissue resolution and multiplanar capabilities compared to CT and ultrasonography.
- MR imaging demonstrates gallbladder wall integrity and defects more effectively and convincingly.
- MR cholangiopancreatography enhances visualization of the biliary tree.
Findings:
- Gallbladder perforation diagnosis is often difficult with standard imaging techniques.
- MR imaging excels in visualizing gallbladder wall defects, aiding in the diagnosis of perforation.
- MR cholangiopancreatography offers improved visualization of biliary tree anatomy.
Implications:
- In suspected cases of acute cholecystitis with inconclusive CT or ultrasound findings, MR imaging is recommended as the imaging modality of choice.
- While potentially not cost-effective as a first-line investigation, MR imaging's diagnostic accuracy for gallbladder perforation is significant.
- This highlights the potential role of advanced MRI techniques in managing complex hepatobiliary conditions.
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