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Thomitrems A and E, two indole-alkaloid isoprenoids from Penicillium crustosum Thom
Thomas Rundberget1, Alistair L Wilkins
1National Veterinary Institute, PO Box 8156 Dep, N-0033, Oslo, Norway. thomas.rundberget@vetinst.no
Phytochemistry
|November 28, 2002
Abstract:
Two indole-alkaloid isoprenoids were isolated from extracts of Penicillium crustosum Thom grown on rice. Their structures were elucidated on the basis of various NMR experiments and by comparison to the structurally related penitrems. The two compounds, designated thomitrem A and thomitrem E, contain a 18(19)-double bond and lack the characteristic penitrem 17(18)-ether linkage.