Related Experiment Video
Updated: Sep 28, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
New technique (the NOW test) for rapid detection of Streptococcus pneumoniae in the nasopharynx
Howard Faden1, Michael Heimerl, Gail Goodman
1Department of Pediatrics, State University of New York, University of Buffalo, Buffalo, New York, USA. hfaden@upa.chob.edu
Abstract:
Although the NOW test was originally introduced as a rapid pneumococcal antigen detection test for use with urine samples, it was successfully adapted to nasopharyngeal samples in the present study. The sensitivity, specificity, positive predictive value, and negative predictive value of the test were 92.2, 97.7, 95.9, and 95.5%, respectively. These results demonstrate that nasopharyngeal colonization with Streptococcus pneumoniae can be documented within 15 min of sample collection.
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