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Dermatofibrosarcoma protuberans treated by micrographic surgery.

A Ah-Weng1, J R Marsden, D S A Sanders

  • 1Skin Oncology Service, University Hospital Birmingham NHS Trust, Birmingham B29 6JD, UK.

British Journal of Cancer
|November 28, 2002
PubMed
Summary
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Micrographic surgery effectively treats dermatofibrosarcoma protuberans, an uncommon skin tumor. This method demonstrated no local recurrence in a study, supporting its use as a primary treatment option.

Area of Science:

  • Dermatology
  • Surgical Oncology
  • Cutaneous Oncology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare skin tumor with a high rate of local recurrence after standard surgical excision.
  • Sub-clinical contiguous growth is presumed to cause recurrence, necessitating precise surgical techniques.

Purpose of the Study:

  • To evaluate the efficacy of micrographic surgery for treating dermatofibrosarcoma protuberans.
  • To assess recurrence rates and outcomes following micrographic surgery for DFSP.

Main Methods:

  • Retrospective study of 21 patients with DFSP treated between April 1995 and March 2000.
  • Micrographically controlled excision was the primary surgical technique employed.
  • Tumor locations included trunk, groin, head and neck, and limbs.

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Main Results:

  • Fifteen patients achieved complete tumor clearance with one micrographic layer; four required two layers.
  • One patient underwent conventional excision for positive margins after micrographic attempts.
  • No DFSP recurrence was observed during a median follow-up of 47 months (range 21-80 months).
  • No correlation was found between tumor size and lateral excision margin.

Conclusions:

  • Micrographic surgery is a highly effective treatment for dermatofibrosarcoma protuberans.
  • The technique significantly reduces local recurrence rates for DFSP.
  • Micrographic surgery should be considered the treatment of choice for DFSP.