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Meningiomas associated with brain metastases.
F Maiuri1, P Cappabianca, G Iaconetta
1Department of Neurosurgery, University "Federico II", Naples, Italy.
Zentralblatt Fur Neurochirurgie
|November 29, 2002
Summary
This study details six patients with co-occurring meningioma and brain metastasis, highlighting surgical outcomes. Differentiating these intracranial tumors is crucial for patient management.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Simultaneous occurrence of meningioma and brain metastasis is rare.
- Malignant tumors, particularly breast cancer, can metastasize to the brain.
- Distinguishing between primary meningioma and metastatic lesions is clinically significant.
Purpose of the Study:
- To report on a series of patients with co-existing meningioma and brain metastasis.
- To discuss the diagnostic and management challenges of these dual intracranial lesions.
- To explore potential pathogenetic links between meningiomas and other cancers.
Main Methods:
- Surgical removal of both meningioma and brain metastasis.
- Histological verification of both tumor types.
- Case series analysis of six patients with simultaneous lesions.
Main Results:
- Primary tumor sites included breast (3), ovary (1), lung (1), and unknown (1).
- Two patients had metastasis within the meningioma, two had metastasis adjacent to the meningioma, and two had distant lesions requiring staged removal.
- Surgical interventions were performed with histological confirmation.
Conclusions:
- The co-occurrence of meningioma and brain metastasis necessitates careful differential diagnosis.
- Metastasis within a meningioma is an uncommon event, reported previously in 50 cases.
- Intracranial masses in cancer patients, especially women with breast cancer, may represent meningiomas.