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Autoimmune progesterone dermatitis.
Tuğba Oskay1, Lale Kutluay, Asli Kaptanoğlu
1Department of Dermatology, Bayindir Medical Centre Ankara, Mesa Park Sitesi, Sedir Apt. Daire: 44, 06450 Oran/Ankara/Turkey. tubaoskay@hotmail.com
European Journal of Dermatology : EJD
|December 3, 2002
Summary
Autoimmune progesterone dermatitis (APD) is a rare skin condition. Treatment with conjugated estrogen successfully resolved symptoms in a patient with this progesterone sensitivity.
Area of Science:
- Dermatology
- Immunology
- Endocrinology
Background:
- Autoimmune progesterone dermatitis (APD) is an uncommon condition.
- It is characterized by skin reactions during the luteal phase of the menstrual cycle.
Observation:
- A 27-year-old woman presented with a 3-year history of recurrent facial skin eruptions.
- Lesions appeared during menstruation and were scaly and erythematous.
- She had no prior exposure to synthetic progesterones.
Findings:
- Intradermal skin testing with progesterone was positive.
- A challenge test with intramuscular progesterone acetate confirmed progesterone sensitivity.
- Diagnosis of APD was confirmed.
Implications:
- Conjugated estrogen therapy was effective in treating the patient.
- The patient experienced no recurrence of facial eruptions at one-year follow-up.
- This case highlights a successful treatment option for APD.