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Brown's Tumor Presenting as a Pathological Humerus Fracture: A Rare Diagnostic Pitfall
L Adithya Narayan1, P Velmurugan1, M R Thirunthaiyan1
1Department of Orthopedic Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Journal of Orthopaedic Case Reports
|July 10, 2026
Summary
Brown's tumor, a rare manifestation of hyperparathyroidism, can mimic aggressive bone lesions. Early biochemical testing is crucial for accurate diagnosis and to prevent misdiagnosis of this metabolic bone disorder.
Area of Science:
- Endocrinology
- Orthopedic Surgery
- Pathology
Background:
- Brown's tumor is a rare skeletal manifestation of long-standing hyperparathyroidism.
- It presents as a focal osteolytic lesion due to increased osteoclastic activity.
- These benign lesions can be mistaken for aggressive bone tumors, especially when associated with pathological fractures.