Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vertebral metastases: assessment with apparent diffusion coefficient.

Andreas M Herneth1, Marcel O Philipp, Jonathan Naude

  • 1Department of Radiology, University of Vienna, AKH-Wien, 8F, Währinger Gürtel 18-20, A-1090 Vienna, Austria. andreas.herneth@univie.ac.at

Radiology
|December 4, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SELECT-CT: Symptom Evaluation, Lesion Estimation, and Curated Triage to CT - A Simple Algorithm to Select the Right Patients for Emergent Code Stroke CT.

AJNR. American journal of neuroradiology·2026
Same author

Non-RVU-Generating Clinical Activities, Their Composition and Influence on Productivity, and Reporting Burden in a Public Hospital Setting.

Journal of medical imaging and radiation oncology·2025
Same author

Commentary: Endovascular repair of type B thoracic aortic dissection using a second-generation single branched stent-graft.

European radiology·2025
Same author

Dynamic pseudo-continuous arterial spin labeling angiography using a 3D-radial multi-spoke spoiled gradient-recalled sequence.

Magnetic resonance in medicine·2025
Same author

Is Radiological Reporting of 'Tension' in Spontaneous Pneumothorax Driving Unnecessary Intervention?

Emergency medicine Australasia : EMA·2025
Same author

Current practice and attitudes in emergency department management of primary spontaneous pneumothorax in Australia and New Zealand: a scenario-based/survey.

Internal medicine journal·2025
Same journal

Erratum for: Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model.

Radiology·2026
Same journal

Erratum for: Associations of MRI-derived Paraspinal IMAT and LMM with Cardiometabolic Risk Factors: Results from a German Cohort.

Radiology·2026
Same journal

Erratum for: Blue Rubber Bleb Nevus Syndrome.

Radiology·2026
Same journal

Redefining the Clinical Role of MRI in Endometrial Cancer Staging.

Radiology·2026
Same journal

To Ablate or Not to Ablate: The Colorectal Liver Metastasis Question.

Radiology·2026
Same journal

The Limits of Radiologic Categorization in Pulmonary Nonsolid Nodules.

Radiology·2026
See all related articles

Apparent diffusion coefficient (ADC) measurements can differentiate vertebral metastases and fractures. This technique enhances the specificity of magnetic resonance imaging for diagnosing vertebral conditions.

Area of Science:

  • Radiology
  • Oncology
  • Orthopedics

Background:

  • Distinguishing vertebral metastases from compression fractures is crucial for patient management.
  • Magnetic resonance imaging (MRI) is a key modality, but differentiation can be challenging.

Purpose of the Study:

  • To evaluate the utility of apparent diffusion coefficient (ADC) measurements in differentiating vertebral metastases from compression fractures.
  • To assess if ADC values can improve the specificity of MRI in patients with suspected vertebral lesions.

Main Methods:

  • Apparent diffusion coefficient (ADC) values were measured in vertebral bodies of 22 patients.
  • Patients had known or suspected vertebral metastases.
  • Statistical analysis was performed to compare ADC values between different lesion types.

Related Experiment Videos

Main Results:

  • Vertebral metastases showed significantly lower ADC values (0.69 x 10(-3) mm2/sec) compared to normal vertebral bodies (1.66 x 10(-3) mm2/sec).
  • Pathologic compression fractures also had significantly lower ADC values (0.65 x 10(-3) mm2/sec) than benign compression fractures (1.62 x 10(-3) mm2/sec).
  • A significant difference (P <.03) was observed between metastatic/pathologic fractures and normal/benign fractures.

Conclusions:

  • ADC measurements can reliably distinguish vertebral metastases and pathologic compression fractures from normal vertebral bodies and benign compression fractures.
  • The use of ADC values may enhance the diagnostic specificity of MRI in evaluating vertebral lesions.
  • This quantitative MRI technique offers potential for improved accuracy in diagnosing vertebral conditions.