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Recent glimpses of the elusive spindle matrix
Kristen M Johansen1, Jorgen Johansen
1Department of Zoology and Genetics, Iowa State University, 3154 Molecular Biology Building, Ames, Iowa 50011, USA. kristen@iastate.edu
Cell Cycle (Georgetown, Tex.)
|December 4, 2002
Abstract:
A stationary spindle matrix has been proposed on theoretical grounds to help mediate force production at the mitotic spindle. Direct molecular evidence for the existence of such a matrix has the potential to profoundly influence our view of the molecular mechanisms leading to chromosome segregation during mitosis. Three recent papers suggest that the spindle matrix may be more than a theoretical idea.