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Peripapillary choroidal neovascularisation in sarcoidosis
C M G Cheung1, O M Durrani, P Stavrou
1Birmingham & Midland Eye Centre, Birmingham, United Kingdom.
Ocular Immunology and Inflammation
|December 4, 2002
Summary
This case report details a rare eye complication of sarcoidosis: peripapillary choroidal neovascularisation. Treatment with corticosteroids and laser successfully improved vision and reduced lesion size.
Area of Science:
- Ophthalmology
- Rheumatology
- Systemic Inflammatory Diseases
Background:
- Sarcoidosis is a multisystem granulomatous disease with varied ocular manifestations.
- Ocular involvement in sarcoidosis commonly includes uveitis and optic nerve disease.
- Peripapillary choroidal neovascularisation (PCNV) is an uncommon finding in ocular sarcoidosis.
Observation:
- A patient with histologically confirmed sarcoidosis presented with isolated PCNV.
- The patient had no clinical or diagnostic evidence of uveitis or optic nerve involvement.
- The PCNV was confirmed and monitored via multimodal imaging.
Findings:
- Treatment with oral corticosteroids led to a reduction in the size of the PCNV.
- Subsequent laser photocoagulation effectively treated the remaining PCNV.
- The combined treatment resulted in significant improvement in the patient's visual acuity.
Implications:
- This case highlights isolated PCNV as a potential, previously unreported, ocular complication of sarcoidosis.
- Early diagnosis and combined therapeutic approach (corticosteroids and laser) can prevent irreversible visual loss.
- Further research is warranted to understand the pathogenesis and incidence of PCNV in sarcoidosis.