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Auto-immune neutropenia occurring in association with malignant melanoma
J D White1, I R J MacPherson, T R J Evans
1Cancer Research UK Department of Medical Oncology, Beatson Oncology Centre, Western Infirmary, Glasgow, G11 6NT, UK. white.jeff@talk21.com
Oncology Reports
|December 7, 2002
Abstract:
Neutropenia is frequently observed in the practice of oncology, usually resulting from the use of cytotoxic drugs. Less frequently, neutropenia is due to infiltration of the bone marrow by malignant disease. Both of these usually cause some depletion of all haematopoietic linages. True isolated neutropenia is, in contrast, a less frequent phenomenon. We report a case of auto-immune neutropenia occurring in a patient with metastatic melanoma, and discuss the differential diagnosis and implications for patient management.