Related Experiment Video
Updated: Aug 26, 2026

Preparation of Silica Nanoparticles Through Microwave-assisted Acid-catalysis
Published on: December 16, 2013
Enhancement of combinatorial chemistry by microwave-assisted organic synthesis
Pelle Lidström1, Jacob Westman, Anthony Lewis
1Personal Chemistry Ltd, Lincoln House, The Paddocks, 347 Cherry Hinton Road, Cambridge, CB1 8DH, UK. pelle.lidstrom@personalchemistry.com
Abstract:
It was in the 1980 s that the first papers in which the use of either combinatorial methods or microwave heating in organic chemistry were published. Unlike combinatorial chemistry, which quite readily became an accepted method, particularly in the pharmaceutical industry, it is only now that microwave heating is truly gaining acceptance. Our aim in this review is to attempt to rationalize this slow acceptance and to show the benefits to be gained by employing microwave heating in tandem with combinatorial chemistry. We will also give a number of examples of successful applications.
Related Concept Videos
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Conjugate Addition of Enolates: Michael Addition
Cycloaddition Reactions: Overview
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
Cycloaddition Reactions: MO Requirements for Thermal Activation
Cycloaddition Reactions: MO Requirements for Photochemical Activation

