Related Experiment Video
Updated: Sep 16, 2026

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Single-Atom Ru on N-Heterocyclic Carbene-Functionalized Hypercrosslinked Polymers for N-Formylation of Amines with
Lulu Dang1,2, Yinfang Gao1,2, Yali Wan3
1Guizhou Provincial Key Laboratory of Green Catalysis and Materials for Resource Conversion, School of Chemistry and Materials Engineering, Liupanshui Normal University, Liupanshui 553004, China.
Abstract:
Catalytic transformation of carbon dioxide (CO2) into high-value-added chemicals represents a promising approach for CO2 emission reduction and utilization. Herein, single-atom ruthenium (Ru) supported on N-heterocyclic carbene (NHC)-functionalized hypercrosslinked polymers were fabricated and applied as recyclable catalysts for the N-formylation of amines using CO2 and H2 as feedstocks. Catalytic evaluations demonstrated that the chemical structure of the NHC ligand had a significant influence on catalytic activity. Specifically, P(PhPy-TPB)-Ru, functionalized with a single pyridine moiety on the NHC ligand, exhibited the optimal catalytic performance, even slightly outperforming its homogeneous counterpart. Furthermore, mechanistic studies indicated that both the base and solvent played pivotal roles in modulating the reaction activity. In particular, the use of methanol as the solvent in the presence of a base significantly enhanced reaction efficiency, which was attributed to the in situ generation of methyl formate as a key intermediate. Notably, the developed catalytic system possessed excellent catalytic efficiency, a broad substrate scope, superior stability, and easy recyclability, allowing the catalyst to be reused for up to eight consecutive cycles without significant loss of catalytic activity.
More Related Videos
Related Concept Videos
Amines to Amides: Acylation of Amines
Next, the second equivalent of amine serves as a Brønsted base and deprotonates the quaternary amide...
Preparation of Amines: Alkylation of Ammonia and Amines
Each alkylation step makes the nitrogen center more nucleophilic, which triggers successive alkylations until a quaternary ammonium salt is formed. Considering...
Preparation of Amines: Reduction of Amides and Nitriles
Amides can be reduced to primary, secondary, and tertiary amines using catalytic hydrogenation, active metals like Fe,...
Preparation of Amines: Reductive Amination of Aldehydes and Ketones
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Mechanism
Nucleophilic Aromatic Substitution: Elimination–Addition

