Coronary artery bypass grafting combined with aortic valve replacement in healthy octogenarians does not increase
Harald Brunvand1, Jon Offstad, Sigurd Nitter-Hauge
1Department of Cardiology, Rikshospitalet, University of Oslo, Norway. harald.brunvand@rikshospitalet.no
Insights
Aortic valve replacement (AVR) with coronary artery bypass grafting (CABG) in octogenarians is safe. Combined AVR and CABG in healthy octogenarians showed no increased postoperative risk compared to isolated AVR.
Area of Science:
- Cardiovascular Surgery
- Geriatric Cardiology
- Thoracic Surgery
Background:
- Aortic stenosis is prevalent in octogenarians, often necessitating surgical intervention.
- The combined procedure of aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) in this age group requires careful risk assessment.
- Indications and outcomes for combined AVR and CABG versus isolated AVR in elderly patients remain debated.
Purpose of the Study:
- To evaluate the postoperative risk of combined AVR and CABG compared to isolated AVR in otherwise healthy octogenarians.
- To assess the safety and efficacy of combined cardiac surgeries in elderly patients with critical aortic stenosis.
Main Methods:
- Retrospective analysis of 94 patients over 80 years old undergoing AVR between 1994-1998.
- Comparison of outcomes between 52 patients who underwent combined AVR and CABG and 42 patients who underwent isolated AVR.
- Data collection from hospital records with a follow-up period of 0-7 years.
Main Results:
- No significant difference in early mortality (9.5% for AVR vs. 7.6% for AVR and CABG; p=NS).
- Similar three-year survival rates between the groups (78.5% for AVR vs. 80.7% for AVR and CABG; p=NS).
- Patients were predominantly in NYHA class III and IV, with preserved left ventricular ejection fraction.
Conclusions:
- Combined AVR and CABG can be safely performed in healthy octogenarians with aortic stenosis.
- Concomitant coronary artery bypass grafting does not appear to increase surgical risk in this specific patient population.
- The findings support the consideration of combined AVR and CABG in select elderly patients.
Objective:
Critical aortic stenosis with or without coronary artery disease is increasingly common in octogenarians. Surgery is the treatment of choice, but indications and results of aortic valve replacement (AVR), particularly when combined with coronary artery bypass grafting (CABG) are debated. We investigated whether the combined procedure of AVR and CABG increased postoperative risk compared with isolated AVR in otherwise healthy octogenarians.
Design:
In the period 1994-1998, AVR was performed in 94 patients above 80 years, the majority in NYHA class III and IV. Combined AVR and CABG was performed in 52/94 patients. The patients were studied retrospectively by collecting data from hospital records and followed for 0-7 years.
Results:
Mean age was 82 +/- 2.3 years, sex (male/female) 33/61, left ventricular ejection fraction 70 +/- 18%, transvalvular peak pressure gradient 63 +/- 20 mmHg and aortic valve area 0.5 +/- 0.2 cm(2). Early mortality (< 30 days) was 4/42 (9.5%) after AVR and 4/52 (7.6%) after AVR and CABG (p = NS between groups). Three-year survival was 33/42 (78.5%) after AVR and 42/52 (80.7%) after AVR and CABG (p = NS between groups).
Conclusion:
AVR with concomitant CABG in octogenarians with aortic stenosis who are otherwise healthy, may be performed without increased risk.
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