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Related Experiment Videos

Brain perfusion and ultrasonic imaging techniques.

Jens Eyding1, Wilko Wilkening, Thomas Postert

  • 1Department of Neurology, Ruhr-University Bochum, D-44791, Bochum, Germany. jeyding@web.de

European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology
|December 10, 2002
PubMed
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Ultrasonic perfusion imaging uses advanced ultrasound contrast agents (ECAs) and specialized techniques to assess blood flow. These methods offer potential for improved acute stroke diagnosis and monitoring due to their accessibility and cost-effectiveness.

Area of Science:

  • Neurosonology
  • Medical imaging
  • Ultrasound technology

Background:

  • Traditional Doppler imaging struggles with low cerebral blood flow velocities.
  • Ultrasonic perfusion imaging combines contrast-specific imaging (CAI) with data acquisition and processing (DAP) for evaluating perfusion kinetics.
  • Ultrasound echo contrast agents (ECAs) are crucial for these techniques.

Purpose of the Study:

  • To provide an overview of ultrasonic perfusion imaging techniques.
  • To highlight recent innovations in CAI and DAP for neurosonology.
  • To discuss the clinical potential of these advanced ultrasound methods.

Main Methods:

  • Utilizes contrast agent-specific ultrasound imaging (CAI) modes.
  • Employs various data acquisition and processing (DAP) techniques tailored to specific CAI, ECAs, and organs.

Related Experiment Videos

  • Incorporates destructive imaging techniques like contrast burst imaging (CBI) and time variance imaging (TVI).

    • Main Results:

    • New DAP techniques combined with destructive imaging improve signal-to-noise ratio for transcranial applications.
    • These methods account for contrast agent kinetics and destruction, overcoming depth dependency.
    • Semi-quantitative parameters can be calculated for perfusion assessment.

    Conclusions:

    • Ultrasonic perfusion imaging shows promise for differentiating normal and pathological perfusion.
    • Techniques like CBI and TVI offer enhanced SNR and depth independence.
    • Given the accessibility and cost-effectiveness of ultrasound, these methods could become standard for acute stroke diagnosis and monitoring.