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Updated: Jun 24, 2026

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
Management of chronic critical limb ischemia
Sanjay Rajagopalan1, P Michael Grossman
1Section of Vascular Medicine, Division of Cardiology, L3119, Women's Hospital 1500, East Medical Center Dr., Ann Arbor, MI 48109-0273, USA. srajagop@umich.edu
Insights
Managing chronic limb ischemia (CLI) is complex. A multidisciplinary team approach, as detailed by the University of Michigan
Area of Science:
- Vascular Medicine
- Cardiovascular Diseases
Background:
- Chronic limb ischemia (CLI) presents significant management challenges.
- Effective CLI treatment necessitates a comprehensive, team-based strategy.
Purpose of the Study:
- To outline a multidisciplinary approach for managing chronic limb ischemia.
- To present the vascular medicine program's strategy at the University of Michigan.
Main Methods:
- Review of the University of Michigan's comprehensive vascular medicine program.
- Description of a multidisciplinary team's approach to CLI management.
Main Results:
- The University of Michigan employs a detailed, multidisciplinary strategy for CLI.
- Fig. 4 illustrates the integrated approach to patient care.
Conclusions:
- A multidisciplinary approach is essential for effective chronic limb ischemia management.
- The University of Michigan's vascular medicine program provides a model for integrated CLI care.
Abstract:
The patient with CLI is challenging and requires a multi-disciplinary approach to effective management that involves a team of individuals proficient in various aspects of vascular disease. Fig. 4 details the approach at the University of Michigan's comprehensive vascular medicine program.
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