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Related Experiment Video

Updated: Dec 26, 2025

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique
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Surgery for hepatocellular carcinoma.

K C Tan1

  • 1The liver centre, Singapore. kctanliver@pacific.net.sg

Journal of Gastroenterology and Hepatology
|December 11, 2002
PubMed
Summary
This summary is machine-generated.

Hepatocellular carcinoma (HCC) treatment options are limited, with surgery offering the best long-term survival. Liver transplantation is increasingly used for HCC patients with cirrhosis, especially with living donor advancements.

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Area of Science:

  • Hepatology and Surgical Oncology

Background:

  • Hepatocellular carcinoma (HCC) presents limited long-term survival options.
  • Surgery, including resection and transplantation, offers the only hope for sustained disease-free survival in HCC patients.
  • Cirrhosis, common in Asian HCC cases, restricts surgical resection eligibility for many patients.

Purpose of the Study:

  • To review the current therapeutic modalities for hepatocellular carcinoma.
  • To highlight the role of surgical interventions, specifically resection and liver transplantation, in managing HCC.
  • To discuss the impact of adult-to-adult living donor liver transplantation on HCC treatment.

Main Methods:

  • Review of current therapeutic modalities for HCC.
  • Analysis of surgical outcomes for HCC resection and transplantation.
  • Discussion of patient selection criteria for surgical interventions.

Main Results:

  • Surgical resection, in selected HCC candidates, can achieve up to 70% 5-year survival.
  • Adult-to-adult living donor liver transplantation is expanding treatment options for HCC patients with decompensating cirrhosis.
  • Despite advancements, surgical resection remains inaccessible for a significant portion of HCC patients due to associated cirrhosis.

Conclusions:

  • Surgical interventions remain the most effective treatment for long-term HCC survival.
  • Liver transplantation, particularly with living donor advancements, is crucial for managing HCC in cirrhotic patients.
  • Further research and improved surgical techniques are needed to expand treatment accessibility for HCC patients.