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Transcriptional regulatory networks and the yeast cell cycle
1Department of Molecular Genetics and Microbiology, Life Science Building, University of Stony Brook, Stony Brook, NY 11794-5222, USA. bfutcher@ms.cc.sunysb.edu
Current Opinion in Cell Biology
|December 11, 2002
Abstract:
A large amount of microarray gene expression data relevant to the yeast cell cycle has been collected, and several hundred genes have been placed into a model transcriptional control network. Genome-wide studies of the location of cell cycle transcription factors, and a variety of computational approaches, have allowed refinement of the model, and at the same time show how other genome-wide data sets may be organised into model networks.