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Benefiting from 'evil': an incipient moral problem in human stem cell research
1Ethics Institute, Dartmouth College, 6031 Parker House, Hanover, NH 03755, USA. Ronald.M.Green@Dartmouth.edu
Bioethics
|December 12, 2002
Summary
Benefiting from unethical practices can make one a moral accomplice. However, using human embryonic stem cells may be permissible for those opposing embryo destruction, as it doesn't necessarily encourage the wrongful act.
Area of Science:
- Bioethics
- Moral Philosophy
- Stem Cell Research
Background:
- The ethical debate surrounding stem cell research often involves the source of the cells, particularly human embryonic stem cells.
- Past ethical discussions have addressed benefiting from research derived from morally questionable sources, such as fetal tissue or Nazi data.
- The therapeutic promise of stem cell research intensifies the need to clarify the moral implications of benefiting from embryo destruction.
Purpose of the Study:
- To analyze the conditions under which benefiting from others' wrongdoing constitutes moral complicity.
- To apply this ethical framework to the use of human embryonic stem cells.
- To determine if individuals who oppose embryo destruction can ethically use stem cells derived from embryos.
Main Methods:
- Philosophical argumentation and ethical analysis.
- Examination of the concept of moral complicity.
- Application of ethical principles to specific scenarios in stem cell research.
Main Results:
- Benefiting from wrongdoing is considered morally wrong under three conditions: agency, encouragement of repetition, or legitimization of the practice.
- The derivation of most human embryonic stem cell lines involves actions that may be considered wrongful by opponents of embryo destruction.
- Using these stem cells may not incur moral blame if it does not meet the established conditions for complicity.
Conclusions:
- Individuals opposing embryo destruction can ethically utilize human embryonic stem cells.
- The ethical permissibility hinges on whether the use of these cells encourages or legitimizes embryo destruction.
- This ethical analysis provides a framework for navigating the moral complexities of stem cell research and its applications.
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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Stem Cell Culture
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Embryonic Stem Cells
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Induced Pluripotent Stem Cells
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
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