Transfusion-related infectious mononucleosis

Pierre Tattevin1, Anne-Claude Crémieux, Diane Descamps

  • 1Department of Infectious Diseases, CHU Pontchaillou, Rennes, France. pierre.tattevin@chu-rennes.fr

Insights

Transfusion-transmitted infections remain a risk despite donor screening. This case highlights transfusion-related infectious mononucleosis, emphasizing Epstein-Barr virus transmission via blood products.

Area of Science:

  • Infectious Diseases
  • Hematology
  • Virology

Background:

  • Blood transfusions are essential medical interventions.
  • Donor screening minimizes but does not eliminate transfusion-transmitted infections.
  • Epstein-Barr virus (EBV) is linked to post-transplant lymphoproliferative disorders.

Observation:

  • A case of infectious mononucleosis was observed following a blood transfusion.
  • The patient developed symptoms consistent with infectious mononucleosis post-transfusion.

Findings:

  • The case suggests a potential transmission of Epstein-Barr virus (EBV) through blood transfusion.
  • Infectious mononucleosis was diagnosed in the recipient.

Implications:

  • The potential for EBV transmission via blood products warrants consideration.
  • This risk is particularly relevant for immunocompromised populations, such as solid-organ transplant recipients.
  • Enhanced vigilance for transfusion-transmitted EBV may be necessary in specific patient groups.

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