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Updated: Aug 11, 2026

Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm
Published on: December 22, 2016
Transfusion-related infectious mononucleosis
Pierre Tattevin1, Anne-Claude Crémieux, Diane Descamps
1Department of Infectious Diseases, CHU Pontchaillou, Rennes, France. pierre.tattevin@chu-rennes.fr
Abstract:
Careful donor selection has reduced but not eliminated the risk of transfusion-transmitted infections. We report a case of transfusion-related infectious mononucleosis. Given the pivotal role of Epstein-Barr virus in the development of lymphoproliferative disorders after solid-organ transplantation, its potential transmission by blood products deserves to be considered in this population.
Insights
Transfusion-transmitted infections remain a risk despite donor screening. This case highlights transfusion-related infectious mononucleosis, emphasizing Epstein-Barr virus transmission via blood products.
Area of Science:
- Infectious Diseases
- Hematology
- Virology
Background:
- Blood transfusions are essential medical interventions.
- Donor screening minimizes but does not eliminate transfusion-transmitted infections.
- Epstein-Barr virus (EBV) is linked to post-transplant lymphoproliferative disorders.
Observation:
- A case of infectious mononucleosis was observed following a blood transfusion.
- The patient developed symptoms consistent with infectious mononucleosis post-transfusion.
Findings:
- The case suggests a potential transmission of Epstein-Barr virus (EBV) through blood transfusion.
- Infectious mononucleosis was diagnosed in the recipient.
Implications:
- The potential for EBV transmission via blood products warrants consideration.
- This risk is particularly relevant for immunocompromised populations, such as solid-organ transplant recipients.
- Enhanced vigilance for transfusion-transmitted EBV may be necessary in specific patient groups.
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