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Long-term follow-up of surgically treated gallbladder cancer patients
1Department of General Surgery, University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
Aims:
Palliative attempts have traditionally led treatment of gallbladder cancer but resection offers the only chance for long-term survival. This study investigates the impact of surgery with curative intent in gallbladder cancer treatment and evaluates prognostic factors for survival.
Methods:
Two hundred and sixty-seven patients were admitted for surgical therapy. Sixty received resection with curative intent and form the basis of this analysis.
Results:
R0 resection (n=45) was a highly significant independent survival predictor (P<0.001). All 5-year survivors (n=10) had tumour-free resection margins. Early T stage (P=0.017) and highly differentiated cancer (P=0.008) had a significant better outcome. Nodal spreading increased by local tumour extension and lymphatic involvement decreased patient survival (P=0.018). Patients' age (>75 years) was without influence on long-term survival.
Conclusions:
Long-term survival is possible both in elderly patients and in advanced cancer.
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