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Arterial stiffness: clinical relevance, measurement, and treatment

J L Izzo1, B E Shykoff

  • 1State University of New York at Buffalo, USA.

Reviews in Cardiovascular Medicine
|December 13, 2002
PubMed

Insights

Arterial stiffness, a known sign of poor prognosis, is linked to aging and hypertension. Recent advances suggest better recognition and treatment of vascular stiffening can improve patient outcomes.

Area of Science:

  • Cardiovascular medicine
  • Gerontology
  • Vascular biology

Background:

  • Arterial stiffness, historically recognized, is associated with aging and systolic hypertension.
  • Despite its prognostic significance, age-related arterial stiffening is often overlooked in clinical practice.
  • Clinicians may underestimate the potential for intervention in vascular stiffening.

Purpose of the Study:

  • To highlight the clinical significance of age-related arterial stiffness.
  • To emphasize the need for improved recognition of vascular stiffening in hypertension management.
  • To suggest that advancements in understanding arterial stiffness will improve patient therapy and outcomes.

Main Methods:

  • Review of historical and contemporary medical literature.
  • Analysis of the association between aging, arterial stiffness, and hypertension.
  • Discussion of recent developments in the clinical recognition and management of vascular stiffening.

Main Results:

  • The link between aging, arterial stiffness, and hypertension is well-established.
  • Age-related arterial stiffening has significant adverse prognostic implications.
  • Current clinical practice may not adequately address the consequences of vascular stiffening.

Conclusions:

  • Improved clinical recognition of age-related vascular stiffening is crucial.
  • Advancements in understanding arterial stiffness offer potential for better therapeutic strategies.
  • Enhanced management of vascular stiffening can lead to improved outcomes for patients with hypertension.

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