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Related Experiment Videos

Methicillin resistant Staphylococcus aureus: a multicentre study.

S Hafiz1, A N Hafiz, L Ali

  • 1Mid-East Medical Center, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|December 17, 2002
PubMed
Summary
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Methicillin-resistant Staphylococcus aureus (MRSA) infections are prevalent in Pakistan

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Staphylococcus aureus is a common cause of infections.
  • Methicillin resistance in Staphylococcus aureus (MRSA) poses a significant treatment challenge globally.
  • Understanding the prevalence of MRSA in Pakistan is crucial for public health strategies.

Purpose of the Study:

  • To investigate the frequency of Methicillin-resistant Staphylococcus aureus (MRSA) infection.
  • To assess MRSA prevalence across major urban centers in Pakistan.
  • To determine the presence of Vancomycin resistance in Staphylococcus aureus isolates.

Main Methods:

  • Collected 792 consecutive Staphylococcus aureus clinical isolates from 8 laboratories nationwide.
  • Utilized Kirby Bauer disc diffusion for antibiotic sensitivity testing.

Related Experiment Videos

  • Determined Vancomycin Minimum Inhibitory Concentration (MIC) using the 'E' test method.

    • Main Results:

    • 42% of Staphylococcus aureus isolates exhibited Methicillin resistance (MRSA).
    • No instances of Vancomycin resistance were detected in any isolates.
    • MRSA prevalence varied significantly across different major cities in Pakistan.

    Conclusions:

    • Methicillin-resistant Staphylococcus aureus (MRSA) is present in the Pakistani population.
    • MRSA incidence rates range from 2% to 61%, with higher rates in major cities.
    • No Vancomycin-resistant Staphylococcus aureus strains were identified in the studied urban areas.