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A new, simple, and selective palladium-catalyzed cleavage of triethylsilyl ethers
Delphine Rotulo-Sims1, Joëlle Prunet
1Laboratoire de Synthèse Organique, UMR CNRS 7652, Ecole Polytechnique, DCSO, F-91128 Palaiseau, France.
Organic Letters
|December 20, 2002
Abstract:
[reaction: see text] A simple procedure for the cleavage of triethylsilyl (TES) ethers in the presence of 10 wt % Pd/C in methanol or 95% ethanol is reported. This method allows selective removal of alkyl TES ethers in the presence of aromatic TES ethers or tert-butyldimethylsilyl (TBS) protecting groups.