Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Apoptosis in disease].

Marcus Schuchmann1, Peter R Galle, Stephan Kanzler

  • 11.Medizinische Klinik und Poliklink der Johannes Gutenberg-Universität Mainz.

Medizinische Klinik (Munich, Germany : 1983)
|December 20, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[DRESS as a rare differential diagnosis in eosinophilia, skin rash and acute hepatitis].

Zeitschrift fur Gastroenterologie·2024
Same author

[Patient safety 4.0: "Failure of the Week" It's all about role modelling!]

Deutsche medizinische Wochenschrift (1946)·2023
Same author

Quality of life as a therapeutic objective in the management of hepatic encephalopathy and the potential role of rifaximin-α.

European journal of gastroenterology & hepatology·2021
Same author

Ramucirumab in patients with previously treated advanced hepatocellular carcinoma: Impact of liver disease aetiology.

Liver international : official journal of the International Association for the Study of the Liver·2021
Same author

Evaluation of a novel colonoscope offering flexibility adjuster - a retrospective observational study.

Therapeutic advances in gastroenterology·2021
Same author

The Role of p53 Dysfunction in Colorectal Cancer and Its Implication for Therapy.

Cancers·2021
Same journal

Medizinische Klinik (Munich, Germany : 1983)·2020
Same journal

Medizinische Klinik (Munich, Germany : 1983)·2020
Same journal

Medizinische Klinik (Munich, Germany : 1983)·2020
Same journal

[Not Available].

Medizinische Klinik (Munich, Germany : 1983)·2016
Same journal

[Not Available].

Medizinische Klinik (Munich, Germany : 1983)·2016
Same journal

[Not Available].

Medizinische Klinik (Munich, Germany : 1983)·2014
See all related articles

Apoptosis, programmed cell death, is vital for development and tissue balance. Dysregulation of this process, involving caspases, can lead to various diseases.

Area of Science:

  • Cell Biology
  • Developmental Biology
  • Molecular Biology

Context:

  • Apoptosis, or programmed cell death, is a fundamental biological process essential for embryonic development and maintaining tissue homeostasis in multicellular organisms.
  • The molecular machinery underlying apoptosis involves a highly conserved intracellular signaling cascade, culminating in the activation of caspases, cysteine-specific proteases.
  • While the core effectors of apoptosis have remained consistent throughout evolution, intricate regulatory mechanisms have evolved significantly.

Purpose:

  • This review examines the clinical relevance of apoptosis.
  • It will detail the key proteins involved in the apoptotic cascade.
  • Furthermore, it will explore diseases associated with disruptions in apoptotic pathways.

Summary:

Related Experiment Videos

  • This review focuses on the clinical implications of apoptosis, a critical cellular process.
  • It elucidates the molecular cascade, including caspases, that governs programmed cell death.
  • The review also investigates diseases linked to the imbalance of cellular life and death pathways.

Impact:

  • Understanding apoptosis is crucial for comprehending numerous diseases.
  • This review provides insights into the molecular basis of cell death.
  • It highlights the clinical significance of apoptotic dysregulation in disease pathogenesis.