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Updated: Sep 28, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person
S D Lawn1, C Wood, D N Lockwood
1Hospital for Tropical Diseases, North Middlesex Hospital, London WC1E 6AU, United Kingdom. stevelawn@yahoo.co.uk
Abstract:
Two months after starting highly active antiretroviral treatment (HAART), an individual with human immunodeficiency virus type 1 (HIV-1) infection and profound CD4+ T lymphocytopenia developed several erythematous plaques on his face, which were due to borderline tuberculoid leprosy with reversal reaction. The temporal association between the development of these lesions and changes in blood CD4+ lymphocyte count and plasma HIV-1 load observed during HAART strongly suggests that the presentation of leprosy resulted from immune reconstitution.
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