Paediatric regional anaesthesia--what makes a difference?

John B Eck1, Allison Kinder Ross

  • 1Division of Paediatric Anaesthesia and Critical Care Medicine, Department of Anaesthesiology, Duke University Medical Center, P.O. Box 3094, Durham, NC 27710, USA.

Insights

Regional anesthesia offers effective post-operative pain control for pediatric ambulatory surgery. This review highlights pediatric-specific anatomy and physiology for successful regional blocks, focusing on long-acting anesthetics and caudal block adjuncts for prolonged analgesia with fewer side effects.

Area of Science:

  • Pediatric Anesthesiology
  • Regional Anesthesia
  • Pain Management

Background:

  • Regional anesthetic techniques are vital for post-operative pain management in pediatric ambulatory surgery.
  • Understanding unique pediatric anatomy and physiology is crucial for successful regional block performance.

Purpose of the Study:

  • To review the effective use of long-acting local anesthetics in children.
  • To explore combinations of local anesthetics and adjunct medications for prolonged caudal blockade.
  • To provide an overview of peripheral nerve blockade in pediatric patients.

Main Methods:

  • Review of literature on pediatric regional anesthesia techniques.
  • Focus on anatomical and physiological considerations in children.
  • Analysis of local anesthetic and adjunct medication combinations for caudal blocks.
  • Examination of peripheral nerve blockade applications in pediatric surgery.

Main Results:

  • Long-acting local anesthetics are effective for pediatric pain control.
  • Specific adjunct medications can prolong caudal blockade duration and efficacy.
  • Peripheral nerve blocks offer viable alternatives for pediatric pain management.

Conclusions:

  • Regional anesthesia, particularly caudal blockade with adjuncts, provides effective and prolonged analgesia for pediatric ambulatory surgery.
  • Consideration of pediatric-specific factors enhances the safety and success of these techniques.
  • Peripheral nerve blockade is a valuable option for tailored pain management in children.

Related Concept Videos

Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.