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Published on: June 17, 2016
[The establishment of testicular fibrosis model in Wistar rats]
Tao Wang1, Yu-Mei Ma, He-Ming Xiu
1Department of Pathology, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Objectives:
To establish the testicular fibrosis model in rats.
Methods:
Wistar rats were divided into control group(n = 12) and model group(n = 40) randomly. Testicular fibrosis model was built with the classical method of establishing experimental autoimmune orchitis (EAO) combined with injecting Bacille Calmette-Guerin (BCG) into left testis.
Results:
The incidence rate of EAO and the rate of testicular fibrosis were 100%, 11.1% and 100%, 81.5% at 80, 140 days after the first infection, respectively.
Conclusions:
The model of rat testicular fibrosis was established successfully.
